Membrane-based mechanisms of mitotic spindle assembly
نویسندگان
چکیده
Chromosome segregation during mitosis is mediated by the mitotic spindle. Formation of this microtubular structure relies on distinct processes such as microtubule nucleation and growth and the consequent focusing of these filaments into spindle poles. Here, we discuss our recent finding that a size-exclusion spindle envelope promotes mitotic fidelity in Drosophila cells in light of distinct spindle assembly mechanisms.
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عنوان ژورنال:
دوره 8 شماره
صفحات -
تاریخ انتشار 2015